RAD51D – A New Hereditary Ovarian Cancer Gene With Important Implications

If you have a compelling family history of ovarian cancer that is not explained by a mutation in the BRCA1 or BRCA2 gene, it is possible that a mutation in the RAD51D gene could be the explanation.

Mechanism of Cisplatin-Resistance in BRCA2-Related Ovarian Cancers

Two papers published online today in the journal Nature (abstracts available here and here) show us why this is the case at least in a subset of cases in individuals with BRCA2 mutations.