The Important Role of Rearrangements, Duplications, and Deletions of BRCA1 and BRCA2 – Part 2

(This is the second part of a series that began with a previous post – “The Important Role of Rearrangements, Duplications, and Deletions of BRCA1 and BRCA2“.) In Part 1 of this series, we provided an introduction to the role that large rearrangements of the BRCA1 and BRCA2 genes play in Hereditary Breast and Ovarian [...]

The Important Role of Rearrangements, Duplications, and Deletions of BRCA1 and BRCA2

(this is the 1st part of a 7 part series) The Hereditary Breast and Ovarian Cancer risk genes, BRCA1 and BRCA2, are the most important genetic risk factors known for breast and ovarian cancer.  Individuals with a disease-associated mutation in one of these genes have markedly elevated breast cancer and ovarian cancer risks.  The identification [...]

Abraxas: A New Hereditary Breast Cancer Gene

If you have a compelling family history of breast cancer that is not explained by a BRCA1 or BRCA2 gene mutation, another gene – Abraxas – has been added to the list of possible explanations.