If you have a compelling family history of breast and ovarian cancer that is not explained by a mutation in the BRCA1 or BRCA2 gene, it is possible that the RAD51C gene could be the explanation. An international research team demonstrated that mutations in RAD51C can lead to hereditary breast and ovarian cancer risk in a paper published online in Nature Genetics yesterday.
RAD51C: A New Hereditary Breast and Ovarian Cancer Gene
Filed Under: BRCA1, BRCA2, Breast Cancer, BRIP1, Cancer Genetics, Common Disease, Rare Gene/Rare Allele Hypothesis, Family History, Fanconi Anemia, Hereditary Breast and Ovarian Cancer, Ovarian Cancer, PALB2, RAD51C Tagged: BRCA2, breast cancer, BRIP1, cancer susceptibility, cancer susceptibility gene, fanconi anemia, Germany, Hereditary Breast and Ovarian Cancer, high througput sequencing, next generation sequencing, ovarian cancer, PALB2, RAD51C, RAD51C Breast Cancer, RAD51C Ovarian Cancer